
OBAGI NU-DERM SYSTEM
NU-DERM TRANSFORM YOUR SKIN FROM THE INSIDE OUT
Sun damage, also known as photodamage, can cause physical and structural changes to the skin, which may lead to age spots, fine lines, and wrinkles. Watch this video for tips on how to help improve pigmentation problems and prevent future damage to your skin with Obagi Nu-Derm® System.
Skin aging is a natural process, but daily sun exposure can contribute to premature aging, slowing down the turnover of skin cells between healthy new cells and old damaged cells. The Nu-Derm System combined with tretinoin* (*Tretinoin cream is indicated for topical application in the treatment of acne vulgaris) is clinically proven to help address the signs of aging in all skin types.
The Nu-Derm System is an anti-aging system that transforms cellular functions in all layers of the skin, helping to make skin look and act younger and healthier.
The Nu-Derm System is an anti-aging therapy that penetrates below the skin’s surface to transform skin cell functions at the cellular level and correct the damage within...revealing healthy, younger-looking skin.
Nu-Derm is ideal if you have:
- Age spots
- Fine lines and wrinkles
- Rough skin
- Skin laxity (loss of elasticity)
- Erythema (redness)
- Sallowness (yellowish complexion)
- Hyperpigmentation (discoloration)
COMPLETE SKIN CARE SYSTEM CUSTOMIZED BY SKIN TYPE
NU DERM SYSTEM FOR NORMAL TO DRY SKIN / NU DERM SYSTEM FOR NORMAL TO OILY SKIN
NU-DERM SYSTEM
Our best-selling, anti-aging skin care system is available in 2 customized sets based on skin type, Normal to Dry Skin and Normal to Oily Skin, and also includes Complementary Products to enhance your skin care routine.


GENTLE CLEANSER
Gently removes makeup and everyday impurities for a clean, fresh complexion.

TONER
Alcohol-free, non-drying toner helps adjust the pH of your skin for increased penetration of product ingredients.

CLEAR
Gentle yet effective prescription-strength hydroquinone helps correct the appearance of age and sun spots for a healthier, more even complexion.

EXFODERM
A lightweight lotion that exfoliates the top layer of the skin, removing dull, old skin cells, while promoting new skin cells for a brighter complexion.

BLENDER
A unique formula containing prescription-strength hydroquinone for the gradual lightening of sun spots, age spots, and other types of discoloration.

HYDRATE
A moisturizing cream to be used as needed to soothe areas of dry, flaky skin.

SUN SHIELD MATTE BROAD SPECTRUM SPF 50
A sunscreen that combines UVB absorption and UVA protection in an elegant matte finish that is non-comedogenic, allergy tested, and dermatologist tested. Sheer, PABA-free, and fragrance-free for all skin types.
NU DERM SYSTEM COMPLEMENTARY PRODUCTS

CLEAR FX
A topical non-prescription formula with a non-hydroquinone skin brightener containing arbutin and antioxidants to help reduce the appearance of age and sun spots.

BLEND FX
A topical non-prescription formula with a non-hydroquinone skin brightener containing arbutin, exfoliants, and antioxidants to help reduce the appearance of age and sun spots.

HEALTHY SKIN PROTECTION SPF 35
A sunscreen with 9% micronized zinc oxide and 7.5% octinoxate that provides broad-spectrum UVA/UVB protection.

PHYSICAL UV BLOCK SPF 32
A sunscreen with 18.5% zinc oxide that provides broad-spectrum UVA/UVB protection.

SUNFADER
With SPF 15, helps to minimize uneven skin tone and brown spots with 4% hydroquinone.

TRETINOIN
A topical cream indicated for application in the treatment of acne vulgaris.

RENOVA
RENOVA (tretinoin cream) 0.02% is indicated as an adjunctive agent for use in the mitigation of fine facial wrinkles in patients who use comprehensive skin care and sunlight avoidance programs. RENOVA DOES NOT ELIMINATE WRINKLES, REPAIR SUN-DAMAGED SKIN, REVERSE PHOTOAGING, or RESTORE MORE YOUTHFUL or YOUNGER SKIN.
RENEW YOUR SKIN
The Nu-Derm System with tretinoin* delivers visible results you’ll love.
CLINICALLY SIGNIFICANT IMPROVEMENTS IN THE SIGNS OF SKIN AGING



2x greater improvement in all measurements of fine lines and wrinkles vs stand-alone treatments3,4 - Clinically significant improvement was seen in facial fine wrinkles, fine wrinkles around the mouth, and loss of elasticity.
RESULTS YOU CAN SEE AND FEEL
In 2 separate studies, a majority of patients reported improvement in skin-related quality-of-life parameters at week 12 after using the Nu-Derm System with tretinoin for melasma2,5:- Embarrassment/self-consciousness
- Feeling unattractive
- Efforts to hide skin discoloration
- Focus on skin discoloration by others
- Effects on social and leisure activities
Transform Your Skin at Every Phase
There are 4 phases to skin transformation. Depending on your skin’s response to the treatment, each phase may last anywhere from 1 week to several weeks.Phase 1. Remove (Weeks 1-6)
Clinical Action | Skin Results |
---|---|
Penetration below the surface of the skin to correct signs of aging and acne flares. The top layer of the skin is exfoliated, removing dull, old skin cells to help promote new skin cells. | Your skin will begin to adapt to the system. Expect to experience itching, dryness, and redness that should subside by the end of phase 2. You will begin to notice a more even-toned apperance of your skin. |
Phase 2. Restart (Weeks 7-12)
Clinical Action | Skin Results |
---|---|
Skin produces normal, healthy cells. Pigment cells are distributing melanin more evenly. | Your skin is now adjusting to the system and you will notice smoother, softer, and clearer skin. Skin is becoming more even toned. |
Phase 3. Refresh (Weeks 13-18)
Clinical Action | Skin Results |
---|---|
Skin cells are in the process of transformation. | Your skin is becoming:
|
Phase 4. Restore (Continued results, with proper maintenance)
Clinical Action | Skin Results |
---|---|
Your skin looks restored.Healthy skin needs to be maitained. | More radiant, even-toned, and resilient-looking skin. |
Tretinoin cream is indicated for topical application in the treatment of acne vulgaris. Results from one study for Nu-Derm Normal to Oily System with 0.025% tretinoin cream and another study for Nu-Derm Normal to Oily System with 0.05% tretinoin cream.
If you experience excessive itching, dryness, or redness, discontinue use of the system and contact your physician. When used under the guidance of your physician, maintenance ensures lasting results.
STEPS TO BEAUTIFUL, HEALTHY-LOOKING SKIN
The Nu-Derm System offers a complete, convenient protocol for treatment at home. Your skin care physician will design a specific protocol that incorporates dosing, frequency, and treatment objectives for your skin.
Morning Routine
Step 1: Gentle Cleanser or Foaming Gel—Massage a small amount of cleanser and water onto the skin. Rinse with lukewarm water and gently pat dry.
Step 2: Toner—Apply in the morning and evening after cleansing. Saturate a cotton pad and gently wipe over face and neck. Do not rinse off.
Step 3: Clear—Squeeze a small amount (approximately 1 to 2 pea-size drops) onto your hands. Apply evenly to the entire face, extending to the hairline, over the ears, and ending with a feathering motion, or as directed by your skin care physician.
Step 4: Exfoderm or Exfoderm Forte—Massage a small amount (approximately 1 to 2 pea-size drops) onto the face until completely absorbed, avoiding the eye area.
Step 5: Hydrate—Apply a small amount evenly to the entire face.
Step 6: Sun Shield Matte Broad Spectrum SPF 50—Apply liberally and evenly to the entire face 15 minutes before sun exposure, and reapply at least every 2 hours. (See product packaging for additional usage instructions and warnings.)
Evening Routine
Step 1: Gentle Cleanser or Foaming Gel—Massage a small amount of cleanser and water onto the skin. Rinse with lukewarm water and gently pat dry.
Step 2: Toner—Apply in the morning and evening after cleansing. Saturate a cotton pad and gently wipe over face and neck. Do not rinse off.
Step 3: Clear—Squeeze a small amount (approximately 1 to 2 pea-size drops) onto your hands. Apply evenly to the entire face, extending to the hairline, over the ears, and ending with a feathering motion, or as directed by your skin care physician.
Step 4: Blender—Apply a small amount (approximately 1 to 2 pea-size drops) evenly to the entire face, or as directed by your physician. May be used with Tretinoin Cream or Renova® Cream as prescribed by your physician.
Step 5: Hydrate—Apply a small amount evenly to the entire face.
OBAGI NU-DERM SYSTEMS FAQs
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